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Zerit is used for:
Treating HIV infection when used in combination with other medicines.
Zerit is a nucleoside analogue antiviral. It blocks the growth of HIV.
Do NOT use Zerit if:
you are allergic to any ingredient in Zerit
you are also taking zidovudine
you are also taking didanosine and hydroxyurea
you have abnormal liver function tests, an enlarged liver, or lactic acidosis
Contact your doctor or health care provider right away if any of these apply to you.
Before using Zerit :
Some medical conditions may interact with Zerit . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have kidney or liver problems, inflammation of the pancreas, gallstones, or problems with tingling or numbness in your hands or feet, or if you drink alcohol
Some MEDICINES MAY INTERACT with Zerit . Tell your health care provider if you are taking any other medicines, especially any of the following:
Didanosine because the risk of side effects, including lactic acidosis, inflammation of the pancreas, or numbness or tingling of the hands or feet, may be increased
Didanosine and hydroxyurea because the risk of severe and sometimes fatal liver problems may be increased
Methadone or zidovudine because they may decrease Zerit 's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Zerit may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Zerit :
Use Zerit as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with Zerit . Talk to your pharmacist if you have questions about this information.
Take Zerit by mouth with or without food.
Continue to take Zerit even if you feel well. Do not miss any doses.
If you miss a dose of Zerit , take it as soon as possible. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use this medicine.
Important safety information:
Zerit does not stop the spread of HIV to others through blood or sexual contact. Use barrier methods of birth control (eg, condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors.
Zerit is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Zerit , even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Zerit . The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.
Hormonal birth control (eg, birth control pills) may not work as well while you are using Zerit . To prevent pregnancy, use an extra form of birth control (eg, condoms).
Lab tests, including liver and kidney function tests, may be performed while you use Zerit . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
PREGNANCY and BREAST-FEEDING: It is not known if Zerit can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zerit while you are pregnant. It is not known if Zerit is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Zerit to the baby.
Possible side effects of Zerit :
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Changes in body fat; constipation; diarrhea; headache; loss of appetite; nausea; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills; dark urine; fever; lactic acid imbalance (general body discomfort, cold feeling, dizziness, lightheadedness, slow or irregular heartbeat); muscle aches or weakness; numbness, tingling, or pain in hands or feet; prolonged nausea and vomiting; rapid breathing; shortness of breath; sore throat; stomach pain; sudden weight loss; unusual tiredness or weakness; weakness in the arms or legs; yellowing of the skin or eyes.
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